A Plague Tale: Innocence is set in 1349, a time in which a terrible plague is ravaging the Kingdom of France. Amicia and her younger brother Hugo are being hotly pursued by the Inquisition, through villages devastated by the disease. On their journey, they will have to join forces with other orphans and evade swarms of rats using fire and light. Aided by the link that binds their fates together, the children will face the darkest days of history in their struggle to survive.